I have this problem now and then, restarting is a pain and thats the only way it stops. I tried killing multiple apps to see when this issue occurs .. but did not help much...

And voila i found something better than a restart : log off and log in

Still a pain but less than restarting.... have fun.. cheers

Or press all arrow keys one by one, more times. Always worked for me.

Win 7/8 who are using 64 bit OS >
This is only solution . Change OS platform for aoc/aok and you will see no crash and mouse/keyboard problems in game.

What others talking about is luck ,like 2/100 it will work with up,up-down,down keys. well this is not solution that remember keys like applying/using cheat in x-box's games.